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Журнал
ISSN: 2411-6467 (Print)
ISSN: 2413-9335 (Online)
Статьи, опубликованные в журнале, представляется читателям на условиях свободной лицензии CC BY-ND

MODIFICATION OF TOXIC ACTION OF KNOWN CYTOSTATICS BY THE COMBINED APPLICATION OF A NEW DERIVATIVE COLCHAMIN K-48 ON STRAIN OF SARCOMA-45 (23-26)



Науки и перечень статей вошедших в журнал:
DOI:
Дата публикации статьи в журнале: 2020/08/20
Название журнала: Евразийский Союз Ученых, Выпуск: 76, Том: 5, Страницы в выпуске: 23-26
Автор: Enikeeva Z.M.
Tashkent, Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology of the Ministry of Health of the Republic of Uzbekistan,
Автор: Kobilov O.R.
Tashkent, Tashkent Medical Academy ,
Автор:
, ,
Анотация: A study of the antitumor activity of cisplatin and cyclophosphamide in an experiment on the tumor strain of sarcoma-45 in the late period after inoculation showed that the preparations show moderate activity from 60 to 80%, but a number of serious side effects are revealed in animals. The combined use of these drugs with a new derivative of colchamine - K-48, which has an immunomodulating effect and stimulates the proliferation of hematopoietic progenitor cells in the experiment, leads to a decrease in their toxic effects and also increases antitumor activity.
Ключевые слова: antitumor activity   chemotherapy toxicity   colchamine derivative   hematopoietic stem cells   sarcoma-45                 
Данные для цитирования: Enikeeva Z.M. Kobilov O.R. . MODIFICATION OF TOXIC ACTION OF KNOWN CYTOSTATICS BY THE COMBINED APPLICATION OF A NEW DERIVATIVE COLCHAMIN K-48 ON STRAIN OF SARCOMA-45 (23-26) // Евразийский Союз Ученых. Медицинские науки. 2020/08/20; 76(5):23-26.

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